Cushing's (HAC) Diagnostic

Species & Test

Dose reminder

Dexamethasone dose: 0.01 mg/kg IV

Low-Dose Dexamethasone Suppression (LDDS)

ug/dL
ug/dL

Used to assess PDH pattern

ug/dL

Positive if >1.5 μg/dL

Interpretation

Low-Dose Dexamethasone Suppression (LDDS)

Enter basal and 8-hour cortisol values.

Next Steps

If LDDS positive: perform abdominal ultrasound to evaluate adrenal glands. If 4h suppression pattern (PDH): consider trilostane or mitotane therapy, or pituitary imaging. If no suppression: consider CT abdomen for adrenal mass. Recheck in 4–6 weeks post-treatment initiation.

This calculator is intended as a guide for use by veterinary professionals only. It is not a substitute for professional interpretation, diagnosis, or treatment. Calculations may not be accurate for all individuals or circumstances. Always use professional judgement and verify all calculations before use in clinical practice.